Active standard | Published: 22/09/2016

ISO/TR 16196:2016

Nanotechnologies — Compilation and description of sample preparation and dosing methods for engineered and manufactured nanomaterials
(Nanotechnologies — Compilation et description de la préparation des échantillons et des méthodes de dosage pour les nanomatériaux d´ingénierie et manufacturés)

Available languages: English

Available design: electronic design (pdf), Print design

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Detail information

Designation: ISO/TR 16196:2016

Publication date: 22/09/2016

Pages: 18

Country: International technical standard

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Anotation

Description / Abstract: ISO/TR 16196:2016 provides guidance regarding the preparation of nanomaterials for eco- and bio- toxicological testing. It provides guidance regarding factors pertaining to sample preparation and dose determination that might be useful in toxicological, including ecotoxicological, testing of engineered and manufactured nanoscale materials. The descriptions of sample preparation method factors for both in vitro and in vivo toxicological testing of engineered and manufactured nanoscale materials include considerations about physico-chemical properties, media, methods for transformation and accumulation studies, health effects and dosimetry. The document is not intended to be a literature review nor a thorough assessment of the quality of the methods or data generated. The document is intended to complement other international efforts. The focus of this document is on factors that might lead to results that are not relevant to safety evaluations. When featured, referenced methods are considered for their general interest and potential applicability. It is likely that most of the described methods are not generally applicable to all nanomaterials but they do demonstrate important factors and limitations that are common for a variety of nanomaterials.

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