Active standard | Published: 30/09/2020

ISO 23921:2020

Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke with an intense smoking regime — Method using LC-MS/MS
(Cigarettes — Dosage des nitrosamines spécifiques du tabac dans le courant principal de la fumée de cigarette avec un régime de fumage intense — Méthode par CL-SM/SM)

Available languages: English

Available design: electronic design (pdf), Print design

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Detail information

Designation: ISO 23921:2020

Publication date: 30/09/2020

Pages: 14

Country: International technical standard

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Anotation

Description / Abstract: This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of cigarette mainstream smoke with the intense smoking regime specified in ISO 20778 by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

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